Facts concerning the novel proteins inserted in BT 176:                1. Cry1Ab proteina.    Commercial preparation of B. thuringiensis has a long history of safe use.b.    Exposure to protein through inhalation and dermal routes is not likely to occur since Btk protein is not volatile and not absorbed by the skinc.    Chemical analysis did not show major changes in the nutritional composition of transgenic crop.d.    Currently available data indicate that most plant pesticide proteins are rapidly degraded to the smaller non-toxic peptides and amino acids in mammalian gastric juicee.    There is no evidence that Cry1Ab is  accumulated in mammalian tissuef.    Western blot analysis demonstrates that Cry1Ab protein is degraded in simulated gastric fluid.g.     No hazardous effects were recorded in mice given single oral gavage dose   of 3283 mg/kg CRY1Abh.    No hazardous effects were recorded in Bobwhite quails dosed with Cry1Ab at the rate of 2000 mg/kg, equivalent to 1.4 mg Cry1Ab protein/ kgm              2. PAT proteina.    Search of Gene banks revealed no known toxins were identified as having sequence homology of PAT.b.     No acetylation of amino acids was detected in PAT.c.   PAT degraded completely within 2 minutes in standard concentration in simulated gastric fluid.d.   PAT protein activity is loss instantaneously and irreversible at 37oC in SGF.Since Btk and PAT proteins are unstable at temperature above 35 to 45 C, not glycosylated, not stable to digestion, not stable to processing and prevalent proteins in food, Cry1Ab and PAT proteins in genetically modified maize are not health concern. The amount of Cry1Ab and PAT proteins in Bt176 maize is below detection level, hence a negligible health concern.