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Gene and DNA Sequence
Record information and status
Record ID
107872
Status
Published
Date of creation
2015-03-24 07:46 UTC (german_bch@bvl.bund.de)
Date of publication
2015-04-13 17:40 UTC (dina.abdelhakim@cbd.int)

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General information
Name of the gene or DNA sequence
CoA-transferase alpha subunit gene
Abbreviation
CS-ipdA-RHOE1
Category of DNA sequence
  • Protein coding sequence
Is the gene / DNA sequence is a synthetic molecule?
No
Donor organism
Donor organism
Rhodococcus equi - RHOE1
Characteristics of the protein coding sequence
Name of the protein expressed by the coding sequence
ipdA - CoA-transferase alpha subunit
Biological function
The gene ipdA (REQ_07170) is an ortholog of rv3551 of Mycobacterium tuberculosis and likewise localized in the cholesterol catabolic gene cluster of its bacterial chromosome of Rhodococcus equi. The encoded protein IpdA (GenBank accession CBH46834) carries the PF01144 signature motif of heterodimeric coenzyme A transferase as well as the COG1788 signature of AtoD, the alpha subunit acetoacetyl-CoA transferase of E. coli. It is thought that IpdA is an alpha subunit of a heterodimeric coenzyme A transferase involved in steroid catabolism, more specific in methylhexahydroindanone propionate degradation. It was shown that the cholesterol catabolism is important for pathogenicity of R. equi.
Related trait(s) or use(s) in biotechnology

Records referencing this document (3)
IDDescription
3record(s) found
Country's Decision or any other Communication1 record
Modified Organism1 record
Risk Assessment1 record