Whether or not a particular level of risk is tolerable depends on the apparent severity of the consequences and the likelihood that it will occur. This, taken in light of previously set levels of acceptable risk with respect to the protection goals and assessment end points, will guide the, will guide the risk assessors towards what would be considered an acceptable estimation of the level of risk.

The outcome of this step is the assessment of the overall risk of the LMO. Once this is achieved, it is helpful to determine, as an internal quality control, whether the risk assessment has met the criteria established at the beginning of the process taking into account also those criteria established in the relevant policies in practice with regard to the protection goals, assessment endpoints and thresholds.