There are several strategies that can be put forward with the view to either prevent the risks posed by the LMO or mitigate the consequences that are likely to arise as a result of the LMO. There are several scientific and agricultural practices that can be used to implement these two concepts such as minimum distance of sowing, seed destruction and limited exposure to susceptible receiving environments.

For LMOs, common risk management strategies have typically been designed to reduce the likelihood of exposure, but depending on the specific case, management options might include a variety of measures that are directly or indirectly related to the LMO. Some examples of risk management strategies for LMOs include: minimum distances from sexually compatible species if there is evidence that gene flow could cause adverse effects, destruction of seeds remaining in the field or of volunteer after harvest, restrictions from introduction into specified receiving environments, etc.

Certain risk assessment steps, particularly the evaluation of likelihood and consequences may need to be re-evaluated to take into account each of the identified risk management strategies since these may affect the estimation of the overall risks.