Open-ended Online Forum on Risk Assessment (2025-2026) - Week 2: 28 April to 5 May

During the second week, the 5 topics indicated in the Table of Contents below will be discussed.

The forum will be moderated by: Ms. Ana Laura Mello from Uruguay and Ms. Anita Anthonysamy from Malaysia.

Participants are requested to keep in mind the process for the identification and prioritization of specific issues of risk assessment of living modified organisms that may warrant consideration contained within annex I to decision CP-9/13.

When posting this information, participants are requested to provide their source of information, indicating if it is coming from a publication, their own work, or other type of source. When sharing publications, it is kindly requested that the URL and DOI links be provided.

The discussions will open on Monday 28 April 2025 at 12 (noon) EDT (Montreal time).

The discussions will close on Monday 5 May 2025 at 11 a.m. EDT (Montreal time).

1. Genome-edited mammals for agriculture
Mr Austein McLoughlin,
SCBD
#12264
Posted on behalf of Ms. Ana Laura Mello
Welcome to the second week of the Open-Ended Online Forum on Risk Assessment and Risk Management.

I would first like to thank all colleagues for their insights and contributions during the first week of the online forum. It is very positive to see such robust discussions and engagement. I am certain this will assist the AHTEG with their work.

For the second week of the online forum, I have the honour of moderating the topics on genome-edited mammals for agriculture, living modified organisms produced through new biotechnologies and living modified organisms for food, feed and processing. Under this thread, we will discuss genome-edited mammals for agriculture.

I trust that my co-moderator and I can count on your continued active engagement on this important topic.

To complement the information submitted by the Parties on this topic, I would like to focus the discussions around the following questions:
1. How does this topic potentially pose challenges to the existing risk assessment frameworks, guidance and methodologies? Do solutions exist?
2. What could be the specific challenges to related to this issue?
3. What are the specific issues concerning this topic?
(i) Is there the potential to cause adverse effects on biodiversity, in particular those that are serious or irreversible, taking into account the urgent need to protect specific aspects of biodiversity, such as an endemic/rare species or a unique habitat or ecosystem, taking into account risks to human health and the value of biological diversity to indigenous peoples and local communities?
(ii) Is there the potential to have an introduction into the environment either deliberately or accidentally?
(iii) Is there the potential to disseminate across national borders?
(iv) Is the LMO already, or are likely to be, commercialized or in use somewhere in the world?
4. Are there existing resources on similar issues that can address this issue or resources that could be adapted to address this need?

When providing information and to support the synthesis, kindly indicate which of the questions information is provided for.

Given the volume of topics to be discussed, there will not be the possibility to extend the online forum. So, I kindly invite you to contribute before the close on Monday 5 May 2025 11 a.m. (Montreal time).

I wish you all productive and fruitful discussions.

Ana Laura Mello
2. Living modified organisms produced through new biotechnologies
Mr Austein McLoughlin,
SCBD
#12263
Posted on behalf of Ms. Ana Laura Mello
Welcome to the second week of the Open-Ended Online Forum on Risk Assessment and Risk Management.

I would first like to thank all colleagues for their insights and contributions during the first week of the online forum. It is very positive to see such robust discussions and engagement. I am certain this will assist the AHTEG with their work.

For the second week of the online forum, I have the honour of moderating the topics on genome-edited mammals for agriculture, living modified organisms produced through new biotechnologies and living modified organisms for food, feed and processing. Under this thread, we will discuss LMOs produced through new biotechnologies.

I trust that my co-moderator and I can count on your continued active engagement on this important topic.

To complement the information submitted by the Parties on this topic, I would like to focus the discussions around the following questions:
1. How does this topic potentially pose challenges to the existing risk assessment frameworks, guidance and methodologies? Do solutions exist?
2. What could be the specific challenges to related to this issue?
3. What are the specific issues concerning this topic?
(i) Is there the potential to cause adverse effects on biodiversity, in particular those that are serious or irreversible, taking into account the urgent need to protect specific aspects of biodiversity, such as an endemic/rare species or a unique habitat or ecosystem, taking into account risks to human health and the value of biological diversity to indigenous peoples and local communities?
(ii) Is there the potential to have an introduction into the environment either deliberately or accidentally?
(iii) Is there the potential to disseminate across national borders?
(iv) Is the LMO already, or are likely to be, commercialized or in use somewhere in the world?
4. Are there existing resources on similar issues that can address this issue or resources that could be adapted to address this need?

When providing information and to support the synthesis, kindly indicate which of the questions information is provided for.

Given the volume of topics to be discussed, there will not be the possibility to extend the online forum. So, I kindly invite you to contribute before the close on Monday 5 May 2025 11 a.m. (Montreal time).

I wish you all productive and fruitful discussions.

Ana Laura Mello
3. Living modified organisms expressing genome editing machinery for pest or pathogen control
Mr Austein McLoughlin,
SCBD
#12262
Posted on behalf of Ms. Anita Anthonysamy
Welcome to the second week of the Open-Ended Online Forum on Risk Assessment and Risk Management.

I would first like to thank all colleagues for their insights and contributions during the first week of the online forum. We have seen such robust discussions and engagement on the online forum platform and  I am anticipating that we can keep the momentum going for this second week of fresh new topics. Your thought contributions will definitely pave a solid base to assist the AHTEG with their work. For participants who have not yet contributed, I strongly encourage you to grab the opportunity this week to throw in your ideas as well.

For the second week of the online forum, I have the honour of moderating the two topics on LMOs expressing genome editing machinery for pest or pathogen control and long term and cumulative effects of genetic constructs and living modified organisms. Under this thread, we will discuss LMOs expressing genome editing machinery for pest or pathogen control.

I trust that my co-moderator and I can count on your continued active engagement on this important topic.

To complement the information submitted by the Parties on this topic, I would like to focus the discussions around the following questions:
1. How does this topic potentially pose challenges to the existing risk assessment frameworks, guidance and methodologies? Do solutions exist?
2. What could be the specific challenges to related to this issue?
3. What are the specific issues concerning this topic?
(i) Is there the potential to cause adverse effects on biodiversity, in particular those that are serious or irreversible, taking into account the urgent need to protect specific aspects of biodiversity, such as an endemic/rare species or a unique habitat or ecosystem, taking into account risks to human health and the value of biological diversity to indigenous peoples and local communities?
(ii) Is there the potential to have an introduction into the environment either deliberately or accidentally?
(iii) Is there the potential to disseminate across national borders?
(iv) Is the LMO already, or are likely to be, commercialized or in use somewhere in the world?
4. Are there existing resources on similar issues that can address this issue or resources that could be adapted to address this need?

When providing information and to support the synthesis, kindly indicate which of the questions information is provided for.

Given the volume of topics to be discussed, there will not be the possibility to extend the online forum. So, I kindly invite you to contribute before the close on Monday 5 May 2025 11 a.m. (Montreal time).

I wish you all productive and fruitful discussions.

Anita Anthonysamy
4. Long term and cumulative effects of genetic constructs and living modified organisms
Mr Austein McLoughlin,
SCBD
#12261
Posted on behalf of Ms. Anita Anthonysamy
Welcome to the second week of the Open-Ended Online Forum on Risk Assessment and Risk Management.

I would first like to thank all colleagues for their insights and contributions during the first week of the online forum. We have seen such robust discussions and engagement on the online forum platform and  I am anticipating that we can keep the momentum going for this second week of fresh new topics. Your thought contributions will definitely pave a solid base to assist the AHTEG with their work. For participants who have not yet contributed, I strongly encourage you to grab the opportunity this week to throw in your ideas as well.

For the second week of the online forum, I have the honour of moderating the two topics on LMOs expressing genome editing machinery for pest or pathogen control and long term and cumulative effects of genetic constructs and living modified organisms. Under this thread, we will discuss long term and cumulative effects of genetic constructs and living modified organisms.

I trust that my co-moderator and I can count on your continued active engagement on this important topic.

To complement the information submitted by the Parties on this topic, I would like to focus the discussions around the following questions:
1. How does this topic potentially pose challenges to the existing risk assessment frameworks, guidance and methodologies? Do solutions exist?
2. What could be the specific challenges to related to this issue?
3. What are the specific issues concerning this topic?
(i) Is there the potential to cause adverse effects on biodiversity, in particular those that are serious or irreversible, taking into account the urgent need to protect specific aspects of biodiversity, such as an endemic/rare species or a unique habitat or ecosystem, taking into account risks to human health and the value of biological diversity to indigenous peoples and local communities?
(ii) Is there the potential to have an introduction into the environment either deliberately or accidentally?
(iii) Is there the potential to disseminate across national borders?
(iv) Is the LMO already, or are likely to be, commercialized or in use somewhere in the world?
4. Are there existing resources on similar issues that can address this issue or resources that could be adapted to address this need?

When providing information and to support the synthesis, kindly indicate which of the questions information is provided for.

Given the volume of topics to be discussed, there will not be the possibility to extend the online forum. So, I kindly invite you to contribute before the close on Monday 5 May 2025 11 a.m. (Montreal time).

I wish you all productive and fruitful discussions.

Anita Anthonysamy
5. Living modified organisms for food, feed and processing
Mr Austein McLoughlin,
SCBD
#12260
Posted on behalf of Ms. Ana Laura Mello
Welcome to the second week of the Open-Ended Online Forum on Risk Assessment and Risk Management.

I would first like to thank all colleagues for their insights and contributions during the first week of the online forum. It is very positive to see such robust discussions and engagement. I am certain this will assist the AHTEG with their work.

For the second week of the online forum, I have the honour of moderating the topics on genome-edited mammals for agriculture, living modified organisms produced through new biotechnologies and living modified organisms for food, feed and processing. Under this thread, we will discuss living modified organisms for food, feed and processing.

I trust that my co-moderator and I can count on your continued active engagement on this important topic.

To complement the information submitted by the Parties on this topic, I would like to focus the discussions around the following questions:
1. How does this topic potentially pose challenges to the existing risk assessment frameworks, guidance and methodologies? Do solutions exist?
2. What could be the specific challenges to related to this issue?
3. What are the specific issues concerning this topic?
(i) Is there the potential to cause adverse effects on biodiversity, in particular those that are serious or irreversible, taking into account the urgent need to protect specific aspects of biodiversity, such as an endemic/rare species or a unique habitat or ecosystem, taking into account risks to human health and the value of biological diversity to indigenous peoples and local communities?
(ii) Is there the potential to have an introduction into the environment either deliberately or accidentally?
(iii) Is there the potential to disseminate across national borders?
(iv) Is the LMO already, or are likely to be, commercialized or in use somewhere in the world?
4. Are there existing resources on similar issues that can address this issue or resources that could be adapted to address this need?

When providing information and to support the synthesis, kindly indicate which of the questions information is provided for. Further, one of the submitting Parties indicated a specific priority related to the human consumption of living modified maize. Thus, I would appreciate if you would also be able to share some inputs related to this as well.

Given the volume of topics to be discussed, there will not be the possibility to extend the online forum. So, I kindly invite you to contribute before the close on Monday 5 May 2025 11 a.m. (Montreal time).

I wish you all productive and fruitful discussions.

Ana Laura Mello