The interactions between these three factors create a unique scenario for each risk assessment that needs to be analysed in the event one of the them changes.

A large portion of the information listed here is usually included in the LMO request triggering the risk assessment. The risk assessors can determine whether or not the information provided is sufficient and adequate for conducting a scientifically sound risk assessment. If needed, they can obtain additional information by, for instance, carrying out their own investigation or requesting it from the applicant.