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Record information and status
Record ID
Date of creation
2012-02-28 16:14 UTC (mwach@ilsi.org)
Date of last update
2012-05-25 18:50 UTC (manoela.miranda@cbd.int)
Date of publication
2012-06-01 19:15 UTC (dina.abdelhakim@cbd.int)

This document is also available in the following languages:
General Information
A Review of the Environmental Safety of the PAT Protein
Center for Environmental Risk Assessment, ILSI Research Foundation
Author’s contact information
1156 Fifteenth Street N.W., Washington D.C. 20005-1743 USA
  • English
  • Spanish
  • Portuguese
Publication date
Summary, abstract or table of contents
This document provides a comprehensive review of information and data relevant to the environmental risk assessment of the protein phosphinothricin-N-acetyl transferase (PAT) produced in genetically engineered (GE) plants by genes isolated from  Streptomyces viridochromogenes (pat gene) or Streptomyces hygroscopicus (bar gene) and presents a summary statement about the environmental safety of this protein. All sources of information reviewed herein were publicly available and include: dossiers presented to regulatory authorities; decision summaries prepared by regulatory authorities; peer-reviewed literature; and product summaries prepared by product developers. Many GE plants contain the  pat gene for use as a selectable marker during development. In those cases, there are one or more additional transgenes contained in the plant and the final product is not necessarily glufosinate tolerant. Although this document will not address these additional genes and phenotypes, their presence should be noted when looking at data on the GE plants that express PAT.
Thematic areas
  • Capacity building
  • LMO use and transboundary movement
Background material to the “Guidance on risk assessment of living modified organisms”
Is this document is recommend as background material for the “Guidance on Risk Assessment of Living Modified Organisms”
Section(s) of the “Guidance on Risk Assessment of Living Modified Organisms” this background material is relevant
Information on Organisms or LMOs
Gene(s) identification
Phosphinothricin N-acetyltransferase gene - Streptomyces viridochromogenes - STRVR
Resistance to herbicides - Glufosinate
Additional Information
Type of resource
  • Article (journal / magazine / newspaper)
Publisher and its location
ILSI Research Foundation
Washington, DC
Keywords and any other relevant information
PAT, bar, phosphinothricin, glufosinate, glufosinate ammonium, herbicide tolerant, genetically engineered, environmental risk assessment