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Record information and status
Record ID
Date of creation
2012-05-09 20:56 UTC (dina.abdelhakim@cbd.int)
Date of publication
2012-05-09 20:56 UTC (dina.abdelhakim@cbd.int)

General Information
Transgenesis has less impact on the transcriptome of wheat grain than conventional breeding
María Marcela Baudo, Rebecca Lyons, Stephen Powers, Gabriela M. Pastori, Keith J. Edwards, Michael J. Holdsworth and Peter R. Shewry
Author’s contact information
Peter R. Shewry
Email: peter.shewry@bbsrc.ac.uk

Rothamsted Research,
Harpenden AL5 2JQ, UK
Fax: +44 (0)1582 763010
  • English
Publication date
Summary, abstract or table of contents

Detailed global gene expression profiles have been obtained for a series of transgenic and conventionally bred wheat lines expressing additional genes encoding HMW (high molecular weight) subunits of glutenin, a group of endosperm specific seed storage proteins known to determine dough strength and therefore bread-making quality. Differences in endosperm and leaf transcriptome profiles between untransformed and derived transgenic lines were consistently extremely small, when analysing plants containing either transgenes only, or also marker genes. Differences observed in gene expression in the endosperm between conventionally bred material were much larger in comparison to differences between transgenic and untransformed lines exhibiting the same complements of gluten subunits. These results suggest that the presence of the transgenes did not significantly alter gene expression and that, at this level of investigation, transgenic plants could be considered substantially equivalent to untransformed parental lines.
Thematic areas
  • Scientific and technical issues
    • Risk assessment
Background material to the “Guidance on risk assessment of living modified organisms”
Is this document is recommend as background material for the “Guidance on Risk Assessment of Living Modified Organisms”
Section(s) of the “Guidance on Risk Assessment of Living Modified Organisms” this background material is relevant
Additional Information
Type of resource
  • Article (journal / magazine / newspaper)
doi: 10.1111/j.1467-7652.2006.00193.x
Publisher and its location
Blackwell Publishing
© 2006 Blackwell Publishing Ltd
12 page PDF
Plant Biotechnology Journal
Keywords and any other relevant information
Keywords: transgenic wheat, transcriptome analysis, substantial equivalence.

Citation: Plant Biotechnology Journal(2006) 4, pp. 369-380