Problem Formulation and Hypothesis Testing for Environmental Risk Assessments of Genetically Modified Crops. (2006) | BCH-VLR-SCBD-103432 | Biosafety Virtual Library Resources | Biosafety Clearing-House

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last updated: 10 May 2012

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Problem Formulation and Hypothesis Testing for Environmental Risk Assessments of Genetically Modified Crops.
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Alan Raybould Email: alan.raybould@syngenta.com Syngenta, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK
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EDP Sciences
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2006
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Environmental Biosafety Research
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© ISBR, EDP Sciences, 2007
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Abstract:

Environmental risk assessments can provide high confidence of minimal risk by testing theories, “risk hypotheses”, that predict the likelihood of unacceptable harmful events. The creation of risk hypotheses and a plan to test them is called problem formulation. Effective problem formulation seeks to maximize the possibility of detecting effects that indicate potential risk; if such effects are not detected, minimal risk is indicated with high confidence. Two important implications are that artificial test conditions can increase confidence, whereas prescriptive data requirements can reduce confidence (increase uncertainty) if they constrain problem formulation. Poor problem formulation can increase environmental risk because it leads to the collection of superfluous data that may delay or prevent the introduction of environmentally beneficial products.
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https://bch.cbd.int/onlineconferences/ra_guidance_references.shtml

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Identifier (ISBN, ISSN, etc.)
DOI: 10.1051/ebr:2007004
Format
7 page PDF
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Keywords: risk assessment / problem formulation / scientific method / certainty / data requirements Citation: Environ. Biosafety Res. 5 (2006) 119–125
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