Proteqflu - equine influenza vaccine | BCH-LMO-SCBD-101612 | Living Modified Organism | Biosafety Clearing-House

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Living Modified Organism (LMO)
  |  
Decisions on the LMO Risk Assessments  
published: 16 Mar 2011 last updated: 18 May 2014
Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
Proteqflu - equine influenza vaccine
EN
Strains vCP2242 and vCP1533
No
"Proteqflu" is a vaccine made from recombinant canary pox virus modified with haemagglutinin gene from Equine Influenza. This LMO is used to vaccinate horses against Equine Influenza.

After inoculation, the viruses do not multiply in the horse but express the protective proteins. As a consequence, these components induce immunity against equine influenza virus (H3N8).
EN
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
EN
  • Proteqflu-Te - equine influenza vaccine
    | Merial | Production of medical or pharmaceutical compounds (human or animal) (Vaccines)
Characteristics of the modification process
pJT006
EN
  • Other (Homologous Recombination)
 
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Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
  • BCH-GENE-SCBD-45883-4 Hemagglutinin gene | Influenza A virus (Influenza, Flu, Avian flu, Human flu, Swine influenza, Equine influenza, Bird flu)
    Protein coding sequence | Production of medical or pharmaceutical compounds (human or animal) (Vaccines)
  • BCH-GENE-SCBD-103890-2 H6 Gene Promoter | Vaccinia virus (Poxvirus, Smallpox vaccine, VACV, VV, Vaccinia)
    Promoter
  • BCH-GENE-SCBD-103891-1 C5 right flanking arm | Canarypox virus (CNPV)
    Plasmid Vector
  • BCH-GENE-SCBD-103892-1 C5 left flanking arm | Canarypox virus (CNPV)
    Plasmid Vector
The following strains of Influenza viruses were used as donor organisms:

Influenza A/equine-2/Ohio/03[H3N8]Canarypox virus (vCP2242 - American strain)and Influenza A/equi-2/Newmarket/2/93 [H3N8] recombinant Canarypox virus (vCP1533 - European strain).
EN
LMO characteristics
EN
  • Vaccine
Detection method(s)
EN
Additional Information
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Records referencing this document Show in search
Record type Field Record(s)
Country's Decision or any other Communication Living modified organism(s) 2
Risk Assessment generated by a regulatory process Living modified organism(s) 1
Living Modified Organism Related LMO(s) 1