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Living Modified Organism
(LMO)
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
Rhizomania resistant, glyphosate tolerant sugar beet
EN
SBVR111 x H7-1
No
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Research Triangle Park, North CarolinaPerson:Syngenta
, United States of AmericaPhone: 919-541-8500,Fax:Related OrganizationSyngenta ()Private sector (business and industry)
SBVR111 x H7-1 sugar beet is produced by conventional breeding crosses of SBVR111 and H7-1 genetically modified sugar beet, and therefore expresses transgenic proteins inherited from single GM sugar beet parent events (from H7-1: CP4 EPSPS, from SBVR111: RZM and PMI).
SBVR111 and H7-1 sugar beet confer resistance to Rhizomania and tolerance to herbicide products containing glyphosate, respectively.
Rhizomania is a disease in sugar beet that is spreading rapidly and is induced by the Beet Necrotic Yellow Vein Virus (BNYVV). SBVR111 sugar beet expresses a gene (RZM) which confers resistance to the disease through interaction with the reproductive system of the virus that will lead to a reduction of the development of the virus in the plant. SBVR111 sugar beet also expresses a Phosphomannose Isomerase (PMI) protein, which acts as a selectable marker enabling transformed plant cells to utilize mannose as a primary carbon source.
H7-1 sugar beet expresses the CP4 EPSPS enzyme which confers the tolerance to glyphosate herbicide.
EN
SBVR111 and H7-1 sugar beet confer resistance to Rhizomania and tolerance to herbicide products containing glyphosate, respectively.
Rhizomania is a disease in sugar beet that is spreading rapidly and is induced by the Beet Necrotic Yellow Vein Virus (BNYVV). SBVR111 sugar beet expresses a gene (RZM) which confers resistance to the disease through interaction with the reproductive system of the virus that will lead to a reduction of the development of the virus in the plant. SBVR111 sugar beet also expresses a Phosphomannose Isomerase (PMI) protein, which acts as a selectable marker enabling transformed plant cells to utilize mannose as a primary carbon source.
H7-1 sugar beet expresses the CP4 EPSPS enzyme which confers the tolerance to glyphosate herbicide.
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
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BCH-LMO-SCBD-101876-3 Living Modified Organism SBVR111 rhizomania resistant sugar beetSyngenta Seeds GmbH | Resistance to diseases and pests (Viruses, Beet necrotic yellow virus (BNYV))
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BCH-LMO-SCBD-14773-14 Living Modified Organism KM-ØØØH71-4 - Roundup Ready™ sugar beetMonsanto | Resistance to herbicides (Glyphosate)
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BCH-ORGA-SCBD-12097-5 Organism Beta vulgaris (Common beet, Sugarbeet, BETMA)Crops
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pSYN15965 and PV-BVGT08
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- Cross breeding
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Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
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BCH-GENE-SCBD-101874-2 Ubiquitin gene 3 promoter | Arabidopsis thaliana (Thale cress, Mouse-ear cress, Arabidopsis, ARATH)Promoter
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BCH-GENE-SCBD-101870-7 RZM Genetic Element | Beet necrotic yellow vein virus (BNYVV)Protein coding sequence | Resistance to diseases and pests (Viruses, Beet necrotic yellow virus (BNYV))
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BCH-GENE-SCBD-100269-8 Nopaline Synthase Gene Terminator | Agrobacterium tumefaciens (Agrobacterium)Terminator
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BCH-GENE-SCBD-101873-3 Heatshock protein 80 gene promoter | Brassica oleracea (Wild cabbage, Crucifers, BRAOL)Promoter
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BCH-GENE-SCBD-15003-7 Phosphomannose Isomerase gene | Escherichia coli (ECOLX)Protein coding sequence | Mannose tolerance,Selectable marker genes and reporter genes
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BCH-GENE-SCBD-100290-6 CaMV 35S terminator | Cauliflower mosaic virus (CaMV)Terminator
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BCH-GENE-SCBD-101416-7 Ti plasmid right border repeat | Agrobacterium tumefaciens (Agrobacterium)Plasmid vector
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BCH-GENE-SCBD-100365-6 Chloroplast transit peptide 2 | Arabidopsis thaliana (Thale cress, Mouse-ear cress, Arabidopsis, ARATH)Transit signal
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BCH-GENE-SCBD-14979-7 5-enolpyruvylshikimate-3-phosphate synthase gene | Agrobacterium tumefaciens (Agrobacterium)Protein coding sequence | Resistance to herbicides (Glyphosate)
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BCH-GENE-SCBD-101877-5 rbcS-E9 gene terminator | Pisum sativum (Garden pea, PEA)Terminator
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BCH-GENE-SCBD-101415-9 Ti plasmid left border repeat | Agrobacterium tumefaciens (Agrobacterium)Plasmid vector
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BCH-GENE-SCBD-101507-5 FMV 34S promoter | Figwort mosaic virus (Figwort mottle virus, FMV, CMoVb)Promoter
DNA insert from SBVR111 vector pSYN15965
RZM gene originated from the Beet Necrotic Yellow Vein Virus (BNYVV). The gene RZM is the inverted repeat of a part of the RNA-1 gene transcript of the BNYVV. This portion of RNA-1 encodes the RNA dependent RNA polymerase (RdRp) or replicase protein. Expression of the RZM, driven by the promoter and intron from the Ubiquitin 3 (Ubi3) gene of Arabidopsis thaliana, confers resistance to BNYVV by targeting the replicase RNA transcript of the infecting virus via the RNAi mechanism.
DNA insert from H7-1 vector PV-BVGT08
H7-1 sugar beet was developed to allow for the use of glyphosate, the active ingredient in the herbicide Roundup®, as a weed control option. This genetically engineered sugar beet line contains a form of the plant enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) that allows it to survive the otherwise lethal application of glyphosate. The EPSPS gene that was introduced into H7-1 was isolated from the common soil bacterium Agrobacterium tumefaciens, strain CP4 and the form of EPSPS enzyme produced by this gene is tolerant to glyphosate.
For additional information on this LMO, please refer to the records of the parental LMOs.
EN
RZM gene originated from the Beet Necrotic Yellow Vein Virus (BNYVV). The gene RZM is the inverted repeat of a part of the RNA-1 gene transcript of the BNYVV. This portion of RNA-1 encodes the RNA dependent RNA polymerase (RdRp) or replicase protein. Expression of the RZM, driven by the promoter and intron from the Ubiquitin 3 (Ubi3) gene of Arabidopsis thaliana, confers resistance to BNYVV by targeting the replicase RNA transcript of the infecting virus via the RNAi mechanism.
DNA insert from H7-1 vector PV-BVGT08
H7-1 sugar beet was developed to allow for the use of glyphosate, the active ingredient in the herbicide Roundup®, as a weed control option. This genetically engineered sugar beet line contains a form of the plant enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) that allows it to survive the otherwise lethal application of glyphosate. The EPSPS gene that was introduced into H7-1 was isolated from the common soil bacterium Agrobacterium tumefaciens, strain CP4 and the form of EPSPS enzyme produced by this gene is tolerant to glyphosate.
For additional information on this LMO, please refer to the records of the parental LMOs.
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- Food
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EN
| Record type | Field | Record(s) | |
|---|---|---|---|
| Country's Decision or any other Communication | LMO identification | 1 | |
| Risk Assessment generated by a regulatory process | Living modified organism(s) | 1 | |
