ArsR gene | BCH-GENE-SCBD-104939 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)

published: 24 Jun 2013 last updated: 08 Aug 2014
General information
ArsR gene
EN
CS-arsR-ECOLX
EN
Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
ArsR Transcriptional Repressor
EN
The gene arsR stems from the E. coli-specific plasmid R773 and encodes for a transcriptional regulator with binding sites for arsenic compounds.

It is a repressor protein that binds to its promoter in the absence of arsenic compounds therefore repressing the expression of downstream genes.

Arsenic compounds that are taken up by bacterial cells form a complex with ArsR, thereby allosterically preventing the association of ArsR with the promoter. Thus, the transcription of downstream genes is induced.
EN
Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 1
Living Modified Organism Genetic elements construct 1