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Genetic element (GENE)
published: 24 Jun 2013
last updated: 08 Aug 2014
ArsR gene
EN
CS-arsR-ECOLX
EN
Protein coding sequence
No
-
BCH-ORGA-SCBD-14930-5 Organism Escherichia coli (ECOLX)Bacteria
ArsR Transcriptional Repressor
EN
The gene arsR stems from the E. coli-specific plasmid R773 and encodes for a transcriptional regulator with binding sites for arsenic compounds.
It is a repressor protein that binds to its promoter in the absence of arsenic compounds therefore repressing the expression of downstream genes.
Arsenic compounds that are taken up by bacterial cells form a complex with ArsR, thereby allosterically preventing the association of ArsR with the promoter. Thus, the transcription of downstream genes is induced.
It is a repressor protein that binds to its promoter in the absence of arsenic compounds therefore repressing the expression of downstream genes.
Arsenic compounds that are taken up by bacterial cells form a complex with ArsR, thereby allosterically preventing the association of ArsR with the promoter. Thus, the transcription of downstream genes is induced.
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