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Genetic element (GENE)
published: 28 Jun 2013 last updated: 16 May 2017
ArsR binding siteEN
ArsR transcriptional repressor binding siteEN
Other (Binding Site)
In the absence of arsenite, the ArsR repressor binds to its DNA binding site and prevents expression of downstream genes. When arsenite enters the cell, binds the ArsR repressor leading to a conformational change which results in the dissociation of the ArsR protein from its binding site. Subsequently, the expression of downstream genes is promoted.