5-enolpyruvylshikimate-3-phosphate synthase gene | BCH-GENE-SCBD-106246 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)

last updated: 20 Dec 2014
General information
5-enolpyruvylshikimate-3-phosphate synthase gene
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CS-aroA-DICDA
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Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
5-enolpyruvylshikimate-3-phosphate synthase (EPSPS)
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Involved in EPSP biosynthesis. The aroA gene, which encodes 5-enolpyruvylshikimate-3-phosphate synthase , an enzyme of the common aromatic biosynthetic pathway, the enzyme participates in biosynthesis of the aromatic amino acids phenylalanine, tyrosine and tryptophan.

The enzyme is a target for herbicides as these amino acids are only synthesized in plants and microorganisms. Glyphosate acts as a competitive inhibitor for phosphoenolpyruvate, as substrate of EPSPS, and is used as a broad-spectrum systemic herbicide.
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Additional Information
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Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 2