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Genetic element
(GENE)
last updated: 30 Jul 2015
Protamine 1 coding sequence
EN
CS-P1-HUMAN
EN
Protein coding sequence
No
-
BCH-ORGA-SCBD-45743-4 Organism Homo sapiens (HUMAN)Mammals
EN
Human Protamine 1
EN
Protamines are polycationic, highly basic polypeptides that bind to DNA and substitute for the somatic histones and transition proteins required for spermatogenesis in vertebrates.
The highly positively charged nature of protamines allows them to electrostatically bind to the negatively charged heparin molecules there fore neutralizing the anticoagulant effects of heparin following cardiovascular surgery.
EN
The highly positively charged nature of protamines allows them to electrostatically bind to the negatively charged heparin molecules there fore neutralizing the anticoagulant effects of heparin following cardiovascular surgery.
EN
- The heparin-protamine interaction. A review. [ English ]
- Protamine - Wikipedia [ English ]
| Record type | Field | Record(s) | |
|---|---|---|---|
| Living Modified Organism | Introduced or modified genetic element(s) | 1 | |
| Living Modified Organism | Genetic elements construct | 1 | |
