Anchored core protein C | BCH-GENE-SCBD-114712 | Genetic element | Biosafety Clearing-House

Loading...
  |  

Genetic element (GENE)

last updated: 21 May 2019
General information
Anchored core protein C
EN
  • Capsid protein C
    EN
ancC
EN
Protein coding sequence
No
Donor organism
Yellow fever virus strain 17 D (vaccine strain)
EN
Characteristics of the protein coding sequence
EN
Anchored protein C (ancC) binds the host cell membrane and gathers the viral RNA genome to form the core of the mature viral particles. During viral entry into the host cell, the protein may induce genome penetration into host cytoplasm. Furthermore, ancC can migrate to the nucleus to modulate host functions.
AncC (nucleotide position 119..481) also contains protein C (nucleotide position 119..421), which is produced upon further processing by the host cell and interferes with host Dicer to prevent RNA interference.
EN
Additional Information
EN
Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 1
Living Modified Organism Genetic elements construct 1