Human alphaherpesvirus 1 (HHV-1, HSV-1, Herpes simplex virus 1) | BCH-ORGA-SCBD-115252 | Organism | Biosafety Clearing-House

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Organism (ORGA)

published: 04 Nov 2019 last updated: 29 Jun 2020
Organism information
Human alphaherpesvirus 1
Kingdom Heunggongvirae
Phylum Peploviricota
Class Herviviricetes
Order Herpesvirales
Family Herpesviridae
Genus Simplexvirus
Species Human alphaherpesvirus 1
  • Human herpes simplex virus 1
  • Human herpesvirus 1
  • HHV-1
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  • HSV-1
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  • Herpes simplex virus 1
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Additional classification
I (double-stranded DNA)
Viruses
Characteristics related to biosafety
East Africa (see attached publication)
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More than 67% of the population is infected.
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Worldwide
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Herpesvirus simplex 1 infects Homo sapiens (Humans). Transmission is predominantly oral-to-oral contact and causes ulcers around the mouth, commonly referred to as "cold sores". Although less common, the virus can also cause genital infections (via oral-genital contact), keratitis (ocular infection) and encephalitis (brain infection). The virus remains latent in the trigeminal ganglia (sensory nerve ganglia).
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Additional Information
Herpes viruses are enveloped viruses, meaning they contain a lipid envelop surrounding a protein core.

Individuals infected with HSV-1 are still at risk for acquiring HSV-2 (genital herpes).
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