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Genetic element (GENE)
published: 09 Dec 2019
last updated: 16 Aug 2022
Acyl-homoserine lactonase SP24
EN
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AHL-lactonaseEN
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AiiA-SP24EN
CS-sp24_aiia-BACTU
EN
Protein coding sequence
No
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BCH-ORGA-SCBD-45614-11 Organism Bacillus thuringiensis (Bt, Bacillus, BACTU)Bacteria
AHL-lactonase SP24 isolated from Bacillus thuringiensis obtained from rice rhizosphere soil.
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Lactonase Enzyme
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The enzyme hydrolyzes N-acyl-homoserine lactones (AHLs) molecules secreted by Gram-negative bacteria, such as Erwinia mallotivora. AHLs have been determined to be the principle signalling molecule involved in quorum sensing (cell-to-cell communication) in Gram-negative bacteria and are essential for survival and regulation of virulence genes. Bacteria lacking AHLs are non-pathogenic.
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Plants modified for quorum quenching (degradation of quorum sensing signalling molecules) have been shown to convey increased protection to bacterial infection.
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