Acyl-homoserine lactonase SP24 | BCH-GENE-SCBD-115339 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)

last updated: 09 Dec 2019
General information
Acyl-homoserine lactonase SP24
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  • AHL-lactonase
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AiiA-SP24
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Protein coding sequence
No
Donor organism
AHL-lactonase SP24 isolated from Bacillus thuringiensis obtained from rice rhizosphere soil.
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Characteristics of the protein coding sequence
Lactonase Enzyme
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The enzyme hydrolyzes N-acyl-homoserine lactones (AHLs) molecules secreted by Gram-negative bacteria, such as Erwinia mallotivora. AHLs have been determined to be the principle signalling molecule involved in quorum sensing (cell-to-cell communication) in Gram-negative bacteria and are essential for survival and regulation of virulence genes. Bacteria lacking AHLs are non-pathogenic.
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Additional Information
Plants modified for quorum quenching (degradation of quorum sensing signalling molecules) have been shown to convey increased protection to bacterial infection.
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Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 1
Living Modified Organism Genetic elements construct 1