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Genetic element (GENE)
last updated: 09 Dec 2019
Acyl-homoserine lactonase SP24
EN
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AHL-lactonaseEN
AiiA-SP24
EN
Protein coding sequence
No
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BCH-ORGA-SCBD-45614-11 Organism Bacillus thuringiensis (Bt, Bacillus, BACTU)Bacteria
AHL-lactonase SP24 isolated from Bacillus thuringiensis obtained from rice rhizosphere soil.
Lactonase Enzyme
EN
The enzyme hydrolyzes N-acyl-homoserine lactones (AHLs) molecules secreted by Gram-negative bacteria, such as Erwinia mallotivora. AHLs have been determined to be the principle signalling molecule involved in quorum sensing (cell-to-cell communication) in Gram-negative bacteria and are essential for survival and regulation of virulence genes. Bacteria lacking AHLs are non-pathogenic.
Plants modified for quorum quenching (degradation of quorum sensing signalling molecules) have been shown to convey increased protection to bacterial infection.
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