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Genetic element (GENE)
last updated: 19 Nov 2020
Other (Leader sequence)
The Tobacco etch virus 5' leader sequence is a translational enhancer to promote expression of downstream sequences. The leader sequence functions in eudicots, but not monocots, and promotes cap-independent translation (mRNA transcripts lack a m7GpppN cap). However, it was noted that a poly(A)-tail must be present for the leader sequence to function.EN
- The tobacco etch viral 5′ leader and poly(A) tail are functionally synergistic regulators of translation.pdf [ English ]
- Identification and Characterization of the Functional Elements within the Tobacco Etch Virus 5′ Leader Required for Cap-Independent Translation.pdf [ English ]
- Compatibility of translational enhancers with various plant species.pdf [ English ]