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Genetic element
(GENE)
published: 09 Jun 2006
last updated: 26 Feb 2014
Beta-lactamase gene
EN
CS-bla-ECOLX
EN
Protein coding sequence
No
-
BCH-ORGA-SCBD-14930-5 Organism Escherichia coli (ECOLX)Bacteria
EN
beta-lactamase
EN
Beta-lactamases are enzymes produced by some bacteria and are responsible for their resistance to beta-lactam antibiotics like penicillins, cephamycins, and carbapenems (ertapenem) (Cephalosporins are relatively resistant to beta-lactamase).
These antibiotics have a common element in their molecular structure: a four-atom ring known as a beta-lactam. The lactamase enzyme breaks that ring open, deactivating the molecule's antibacterial properties
EN
These antibiotics have a common element in their molecular structure: a four-atom ring known as a beta-lactam. The lactamase enzyme breaks that ring open, deactivating the molecule's antibacterial properties
EN
| Record type | Field | Record(s) | |
|---|---|---|---|
| Living Modified Organism | Introduced or modified genetic element(s) | 27 | |
| Living Modified Organism | Genetic elements construct | 10 | |
| Laboratory for detection and identification of LMOs | Genetic element(s) detectable by the laboratory | 1 | |