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Genetic element
(GENE)
last updated: 04 Feb 2022
Doublesex splicing module
EN
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Female-specific splicing moduleEN
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female-specific doublesex splicing moduleEN
CS-dsx_splicing-module-SPOFR
EN
Other (splicing module)
No
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BCH-ORGA-SCBD-259116-2 Organism Spodoptera frugiperda (Fall armyworm) This document has been updated. This is not the latest published version. Click here to view the latest version of the record.Insects
EN
The doublesex (dsx) splicing module allows for the female-specific splicing and expression. The module consists of dsx exons 2, 3, 3a, 4b, 4 and 5, together with dsx introns 2, 3 and 4. In females, the splicing results in transcripts containing either exons 2,3,4 and 5 or exons 2, 3a, 4 and 5 in frame with downstream sequences. In males, alternative splicing produces a transcript containing exons 2 and 5. However, unlike the female transcripts, the male transcripts have a frame-shift and are expected to be in frame with a stop codon within exon 5. Thus, transcripts in males are likely degraded by nonsense-mediated decay.
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