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Genetic element
(GENE)
published: 15 Aug 2024
last updated: 16 Jul 2025
Cry1Bb
EN
-
cryI ET5EN
CS-cry1Bb-BACTU
EN
Protein coding sequence
No
-
BCH-ORGA-SCBD-45614-11 Organism Bacillus thuringiensis (Bt, Bacillus, BACTU)Bacteria
EN
Crystal protein Cry1Bb
EN
The Cry1Bb is a crystal delta-endotoxin that is produced by Bacillus thuringiensis. The toxin domain is located at the N-terminus of the protein and likely has a similar mode of action to other crystal proteins. Thus, it binds proteins in the epithelial gut lining of feeding larvae and oligomerizes to form pores, which then allows for an influx of water, cell swelling and eventual lysis. This leads to the destruction of the larval midgut epithelium and death of susceptible larvae. The protein is active on Lepidoptera, specifically family Geometridae.
EN
EN
- GenBank: WYV66140.1 - Cry1Bb [Agrobacterium tumefaciens] [ English ]
- UniProtKB - Pesticidal crystal protein Cry1Bb [ English ]
- Toxicity, Binding, and Permeability Analyses of Four Bacillus thuringiensis Cry1 δ-Endotoxins Using Brush Border Membrane Vesicles of Spodoptera exigua and Spodoptera frugiperda.pdf [ English ]
- GenBank: L32020.1 - Bacillus thuringiensis crystal protein (cryI ET5) gene, complete cds [ English ]
- GenBank: AAA22344.1 - crystal protein [Bacillus thuringiensis] [ English ]
| Record type | Field | Record(s) | |
|---|---|---|---|
| Living Modified Organism | Introduced or modified genetic element(s) | 5 | |
| Living Modified Organism | Genetic elements construct | 5 | |
