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Genetic element
(GENE)
last updated: 15 Aug 2024
Cry2Aa
EN
CS-cry2Aa-BACTU
EN
Protein coding sequence
No
-
BCH-ORGA-SCBD-45614-11 Organism Bacillus thuringiensis (Bt, Bacillus, BACTU)Bacteria
EN
Crystal protein Cry2Aa
EN
Crystal protein Cry2Aa is a crystal delta-endotoxin that is produced by Bacillus thuringiensis. The protein has a molecular weight of roughly 71 kDa (633 amino acids). The toxin domain is located at the N-terminus of the protein and likely has a similar mode of action to other crystal proteins. Thus, it binds proteins in the epithelial gut lining and oligomerizes to form pores, which then allows for an influx of water, cell swelling and eventual lysis. This leads to the destruction of the larval midgut epithelium and death of susceptible larvae. The protein is active on both Lepidoptera (e.g., Geometridae) and Dipteran pests.
EN
EN
| Record type | Field | Record(s) | |
|---|---|---|---|
| Living Modified Organism | Introduced or modified genetic element(s) | 4 | |
| Living Modified Organism | Genetic elements construct | 4 | |
