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Genetic element (GENE)
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last updated: 20 Oct 2025
General information
Cry1B.2
EN
CS-cry1Be_1Ka_1Ab-SYNTH
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Protein coding sequence
Yes
Donor organism
EN
Characteristics of the protein coding sequence
Cry1B.2 protein
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Cry1B.2 is a full-length, insecticidal protein consisting of 1187 amino acids with a molecular weight (MW) of 135 kDa. It is a chimeric protein that consists of domains I and II from Cry1Be, domain III from Cry1Ka2, and the C-terminal domain from Cry1Ab from various subspecies of soil bacterium Bacillus thuringiensis. The production of the Cry1B.2 protein in soybean provides protection against lepidopteran pests. It acts by forming non-specific, ion conducting pores in the apical membrane of midgut epithelial cells, which causes a disruption of the midgut epithelium and leads to death.
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Additional Information
EN
Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 1
Living Modified Organism Genetic elements construct 1