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Genetic element
(GENE)
published: 22 Oct 2007
last updated: 20 Oct 2025
Phytophthora infestans Resistance gene 1
EN
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CS-Rpi-blb1EN
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Rpi-blb1 (Blb1)EN
CS-rpi1-SOLBU
EN
Protein coding sequence
No
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BCH-ORGA-SCBD-12108-3 Organism Solanum bulbocastaneum (Nightshade, Ornamental nightshade)Plants
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Resistance gene 1
EN
The Resistance gene is a member of the NBS-LRR (Nucleotide Binding Site - Leucine Rich Repeat) class and codes for a protein that recognizes specific proteins of Phytophthora infestans termed elicitor proteins which are the causing agent of late-blight disease.
Upon binding this effector, Rpi-blb1 undergoes ATP-dependent conformational change via its functional domain, Nucleotide-binding and Apaf-1, R-protein, and CED-4 (NB-ARC). Recognition of the elicitor proteins will lead to local plant cell death and will thus prevent further development of the pathogen Phytophthora infestans.
EN
Rpi-blb1 is used to confer resistance to late blight disease caused by Phytophthora infestans.
- Transgenic Res (2011): Functional stacking of three resistance genes against Phytophthora infestans in potato [PDF] [ English ]
- The Plant Journal (2003): The R1 gene for potato resistance to late blight (Phytophthora infestans) belongs to the leucine zipper, NBS, LRR class of plant resistance genes [PDF] [ English ]
- The Plant Journal (2003): An ancient R gene from the wild potato species Solanum bulbocastanum confers broad-spectrum resistance to Phytophthora infestans in cultivated potato and tomato [PDF] [ English ]
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