Apyrase-gene | BCH-GENE-SCBD-48365 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)

published: 05 Mar 2009 last updated: 06 Jul 2012
General information
Apyrase-gene
EN
CS-apyrase
EN
Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
Apyrase
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Apyrases are enzymes that transform NTP (nucleoside triphosphates) via NDP to NMP without triggering an endergonic reaction in the process. These enzymes have been identified in the tissues of animals, plants (among others in Arabidopsis thaliana, legumes and potatoes) and fungi and apparently have predominantly regulatory functions.

Double knockout mutations of both apyrase genes from A. thaliana inhibit pollen germination and give rise to male sterile plants. Apyrases play a role in the formation of nodules in leguminous plants, and are also thought to be involved in phosphate uptake. 

Regulation of transporters that, amongst other things, facilitate the transport of xenobiotics out of the plant cell has been demonstrated for plant apyrases. The blocking of apyrase by specific inhibitors increases the sensitivity of the plants to different herbicides, as well as the concentration of the applied herbicides in the plants.  Over-expression of the apyrase psNTP9 from Pisum sativum in A. thaliana increases the resistance of the plants to herbicides and phytohormones.

Apyrase activity in the potato tubers is very high and is probably localised in the area of the cell wall. Together with other enzymes that influence the ATP/ADP/AMP ratio, apyrase activity is suspected to have a regulatory effect on starch biosynthesis in the potato tubers.
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Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 1
Living Modified Organism Genetic elements construct 1