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Genetic element
(GENE)
last updated: 21 May 2019
Nonstructural protein 5
EN
NS5
EN
Protein coding sequence
No
-
BCH-ORGA-SCBD-114710-2 Organism Yellow fever virus (YFV 17D)Viruses
Yellow fever virus strain 17D (vaccine strain)
EN
EN
Nonstructural protein 5 (NS5) encodes a RNA-dependent RNA polymerase required for viral genome replication and capping of the 5' end of the viral genome. Additionally, NS5 also inhibits the interferon alpha/beta signalling pathway via the binding and inactivation of interferon-activated STAT2.
EN
EN
- UniProtKB - YFV polyprotein [ English ]
| Record type | Field | Record(s) | |
|---|---|---|---|
| Living Modified Organism | Introduced or modified genetic element(s) | 1 | |
| Living Modified Organism | Genetic elements construct | 1 | |
