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Genetic element (GENE)
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last updated: 08 Nov 2019
General information
delta-6 elongase
EN
  • polyunsaturated fatty acid specific elongation enzyme 1
    EN
  • Δ6‐elongase
    EN
  • C18 Δ6-polyunsaturated fatty acid elongase
    EN
D6E (PSE1)
EN
Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
EN
Delta-6 elongase is involved in the biosynthesis of polyunsaturated fatty acids and catalyzes the addition of two carbon-hydrogen groups to the carboxyl end of γ-linolenic acid, converting it to dihomo-γ-linolenic acid.

Reactions:
malonyl-CoA + γ-linolenoyl-CoA + H+ → 3-oxodihomo γ-linolenoyl-CoA + CO2 + coenzyme A

malonyl-CoA + stearidonoyl-CoA + H+ → (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + CO2 + coenzyme A
EN
Additional Information
The sequence encodes a protein of 290 amino acids with an approximate weight of 34 kDa.
EN
Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 1
Living Modified Organism Genetic elements construct 1