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Genetic element (GENE)
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last updated: 06 May 2020
General information
Nuclear export protein
EN
  • Nonstructural protein 2
    EN
  • NS2
    EN
NEP
EN
Protein coding sequence
No
Donor organism
  • BCH-ORGA-SCBD-45782-7 Organism Influenza A virus (Influenza, Flu, Avian flu, Human flu, Swine influenza, Equine influenza, Bird flu)
    Viruses
EN
Characteristics of the protein coding sequence
EN
Nuclear export protein (NEP) mediates the nuclear export of viral genomic RNAs, acting as an adaptor between the ribonucleoproteins (RNP; genomic RNA and nucleoprotein) and the host export machinery. The C-terminus of the protein binds to matrix protein 1 (M1), stabilizing the M1-RNP interaction. NEP may stimulate viral cRNA synthesis through the action of viral small RNAs and may recruit host F1F0 ATPase during budding.
EN
Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 1
Living Modified Organism Genetic elements construct 1