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Living Modified Organism
(LMO)
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
Supertilapia
EN
IG-91/03F70
No
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Organization:Centro de Ingeniería Genética y Biotecnología (CIGB)Ave. 31 No.15802 between 158 y 190, Cubanacán, PlayaHavana,
C.P. 11600, P.O. Box 6162, CubaPhone: (53) 7-2504101, (53) 7-2716022,Fax:Website: https://www.cigb.edu.cu/en/about-us/,
Supertilapia is a hybrid tilapia (Oreochromis hornorum x Oreochromis aureus) modified for enhanced growth. The transgenic fish expresses an additional copy of the tilapia growth hormone to induce faster and increased growth in comparison to the wild-type hybrid tilapia. During development, it was observed that supertilapia grow roughly 82% larger compared to their non-transgenic counterparts.
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
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BCH-ORGA-SCBD-100302-4 Organism Oreochromis hornorum x Oreochromis aureus (Hybrid tilapia)Fish
EN
E3000tiGH15
EN
- Microinjection
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0.750 kb
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0.847 kb
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0.850 kb
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Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
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BCH-GENE-SCBD-103749-1 Human Cytomegalovirus promoter | Human betaherpesvirus 5 (Human cytomegalovirus, HCMV, HHV-5)Promoter
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BCH-GENE-SCBD-103642-2 Transcription termination factor | Macaca mulatta polyomavirus 1 (SV40, Simian vacuolating virus 40, simian virus 40, Rhesus macaque polyomavirus)Terminator
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BCH-GENE-SCBD-103750-1 Tilapia Growth Hormone gene | Oreochromis hornorum x Oreochromis aureus (Hybrid tilapia)Protein coding sequence | Changes in physiology and/or production (Growth rate)
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BCH-GENE-SCBD-114748-3 SV40 poly-adenylation signal | Macaca mulatta polyomavirus 1 (SV40, Simian vacuolating virus 40, simian virus 40, Rhesus macaque polyomavirus)Terminator
The modified hybrid tilapia contains one gene cassette for the expression of Oreochromis hornorum x Oreochromis aureus tilapia growth hormone. The tilapia growth hormone coding sequence is under control of the human cytomegalovirus promoter and the Macaca mulatta polyomavirus 1 (SV40) terminator. The promoter additionally contains an enhancer and thus high levels of transcription from this cassette are expected.
EN
- Food
EN
EN
