Modified cecropin peptide coding sequence | BCH-GENE-SCBD-106264 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)
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BCH-GENE-SCBD-106264-1   |   PDF   |   Print   |  
 
last updated: 09 Jan 2015
General information
Modified cecropin peptide coding sequence
EN
CS-CEMA-SYNTH
EN
Protein coding sequence
Yes
Characteristics of the protein coding sequence
Modified cecropin peptide
EN
Cecropins are antimicrobial peptides. Cecropins lyse bacterial cell membranes; they also inhibit proline uptake and cause leaky membranes. Cationic antimicrobial peptides which include cecropin also possess antiviral and fungicidal activity.
EN
Additional Information
This modified Cecropin A peptide is a synthetic molecule designed through molecular modelling. It includes the eight N-terminal amino acids of cecropin A from Hyalophora cecropia (Northern Silkworm) caterpillars and the eighteen C-terminal  amino acids of melittin from Apis mellifera (Western Honey Bee), as well as two additional positively-charged amino acid residues at the C-terminus of the molecule.
EN
Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 1