CoA-transferase alpha subunit gene | Rhodococcus equi (RHOE1) | BCH-GENE-SCBD-107872 | Genetic element | Biosafety Clearing-House

Loading...
  |  
BCH-GENE-SCBD-107872-1   |   PDF   |   Print   |  

Genetic element (GENE)

last updated: 24 Mar 2015
General information
CoA-transferase alpha subunit gene
EN
CS-ipdA-RHOE1
EN
Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
ipdA - CoA-transferase alpha subunit
EN
The gene ipdA (REQ_07170) is an ortholog of rv3551 of Mycobacterium tuberculosis and likewise localized in the cholesterol catabolic gene cluster of its bacterial chromosome of Rhodococcus equi. The encoded protein IpdA (GenBank accession CBH46834) carries the PF01144 signature motif of heterodimeric coenzyme A transferase as well as the COG1788 signature of AtoD, the alpha subunit acetoacetyl-CoA transferase of E. coli. It is thought that IpdA is an alpha subunit of a heterodimeric coenzyme A transferase involved in steroid catabolism, more specific in methylhexahydroindanone propionate degradation. It was shown that the cholesterol catabolism is important for pathogenicity of R. equi.
EN
Records referencing this document Show in search
Record type Field Record(s)
Loading...