delta-6 elongase | Physcomitrella patens - spreading earthmoss, physcomitrella moss | BCH-GENE-SCBD-115269 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)

last updated: 08 Nov 2019
General information
delta-6 elongase
EN
  • polyunsaturated fatty acid specific elongation enzyme 1
    EN
  • Δ6‐elongase
    EN
  • C18 Δ6-polyunsaturated fatty acid elongase
    EN
D6E (PSE1)
EN
Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
EN
Delta-6 elongase is involved in the biosynthesis of polyunsaturated fatty acids and catalyzes the addition of two carbon-hydrogen groups to the carboxyl end of γ-linolenic acid, converting it to dihomo-γ-linolenic acid.

Reactions:
malonyl-CoA + γ-linolenoyl-CoA + H+ → 3-oxodihomo γ-linolenoyl-CoA + CO2 + coenzyme A

malonyl-CoA + stearidonoyl-CoA + H+ → (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + CO2 + coenzyme A
EN
Additional Information
The sequence encodes a protein of 290 amino acids with an approximate weight of 34 kDa.
EN
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