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Genetic element
(GENE)
published: 07 Jan 2020
last updated: 04 Feb 2022
Ubiquitin
EN
CS-ubi-DROME
EN
Protein coding sequence
No
-
BCH-ORGA-SCBD-103760-2 Organism Drosophila melanogaster (Common Fruit Fly)Insects
EN
EN
Ubiquitin is a small protein of 76 amino acids, which is highly conserved in eukaryotes and may have many roles within the cell. Covalent attachment of ubiquitin can mark a protein for proteasomal degradation.
EN
Drosophila melanogaster ubiquitin is an N-terminal peptide, which acts as a "spacer" in the translated polypeptide and is cleaved out to separate/release the connected protein. Ubiquitin also promotes higher expression of the linked protein, likely through improving protein stability and/or folding.
EN
- FlyBase - UBIQUITIN [ English ]
- [Large PDF - 14 MB] - Thesis - Genetic control of agricultural pests (see page 160) [ English ]
- Ubiquitin-fusion protein system a powerful tool for ectopic protein expression in mammalian cells.pdf [ English ]
- Ubiquitin Fusion Technique and Related Methods.pdf [ English ]
| Record type | Field | Record(s) | |
|---|---|---|---|
| Living Modified Organism | Introduced or modified genetic element(s) | 2 | |
| Living Modified Organism | Genetic elements construct | 2 | |