Glycoprotein Gc | Rift Valley fever phlebovirus - RVFV | BCH-GENE-SCBD-115613 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)

last updated: 18 Jun 2020
General information
Glycoprotein Gc
EN
  • Glycoprotein G1
    EN
  • Carboxy-terminus glycoprotein
    EN
Gc
EN
Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
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Rift Valley Fever Virus glycoproteins Gn and Gc are the major structural antigens found on the virion particle. Together the two proteins are present as heterodimers and form the icosahedral shell of the virion. In vitro Gn and Gc form virus-like particles and can induce immunity in animals. Baculovirus expression systems expressing only Gc results in highly pleiomorphic virus-like particles. Thus, for homogeneous virus particle surfaces, heterodimer expression (Gn) is required.
EN
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