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Genetic element (GENE)
last updated: 12 Feb 2021
Protein coding sequence
The enzyme participates in biosynthesis of the aromatic amino acids phenylalanine, tyrosine and tryptophan. The enzyme is a target for herbicides as these amino acids are only synthesized in plants and microorganisms. Glyphosate acts as a competitive inhibitor for phosphoenolpyruvate, as substrate of EPSPS, and is used as a broad-spectrum systemic herbicide.EN
- Safety evaluation of the double mutant 5-enol pyruvylshikimate-3-phosphate synthase (2mEPSPS) from maize that confers tolerance to glyphosate herbicide in transgeneic plants.pdf [ English ]
- 5—Enolpyruvylshikimate 3—Phosphate Synthase: From Biochemistry to Genetic Engineering of Glyphosate Tolerance [ English ]
- Mutated 5-enolpyruvylshikimate-3-phosphate synthase - Patent [ English ]