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Living Modified Organism
(LMO)
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Genome-edited drought tolerant maize
EN
H1L
No
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- Organization: VIB - Flanders Interuniversity Institute for Biotechnology () | BCH-CON-SCBD-42293-1Organization:VIB - Flanders Interuniversity Institute for Biotechnology ()Rijvisschestraat 120 9052 Zwijnaarde, Belgium Tel.: +09 244 66 11,
,Phone:Fax: +09 244 66 10,Email: vib@vib.be,Website: www.vib.be,
The drought-tolerant maize was obtained through CRISPR-Cas genome editing, which resulted in the deletion in the histone H1-like gene and knocking it out. This gene is involved in growth regulation during drought conditions. Thus, the knock out line of maize grows better under conditions of drought.
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
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BCH-ORGA-SCBD-246-6 Organism Zea mays (Maize, Corn, MAIZE)Crops
Inbred line B104
EN
pMHb_ H1L
EN
- Gene editing (e.g. CRISPR-Cas, etc.)
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
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BCH-GENE-SCBD-277321-1 Histone H1-like | Zea mays (Maize, Corn, MAIZE)Protein coding sequence | Tolerance to abiotic stress (Drought)
The maize was genome edited to introduce a deletion in the coding sequence of histone H1-like. This deletion disrupted the gene, thus knocking out its function. The maize line is not expected to have any CRISPR-Cas or selectable markers (hygromycin B phosphotransferase and spectinomycin adenyltransferase) present in the genome due to backcrossing with the B104 inbred line.
EN
- Research
EN
EN
| Record type | Field | Record(s) | |
|---|---|---|---|
| Risk Assessment generated by a regulatory process | Living modified organism(s) | 1 | |
