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Organism
(ORGA)
last updated: 20 Feb 2025
Thosea asigna virus
| Realm | Riboviria |
| Kingdom | Orthornavirae |
| Family | Permutotetraviridae |
| Genus | Alphapermutotetravirus |
| Species | Thosea asigna virus |
- Setothosea asigna virus
- Alphapermutotetravirus thoseae
-
THAVEN
IV ((+)ssRNA)
Viruses
Wild
EN
EN
EN
EN
Thosea asigna virus infects stinging nettle slug caterpillar (Setothosea asigna).
- Research
- Other (Pathogen)
Note: The acronym "THAV" was chosen to avoid confusion with Tomato aspermy virus (commonly used acronym TAV) and for use in the name of genetic elements according to the genetic element thesaurus.
In the field of genetic engineering, the virus is known for its 2A-like self-processing sequence of the capsid precursor protein. It allows for the generation of a multi-protein mRNA transcripts (polycistronic expression) by acting as a separator between proteins. Upon translation, peptide bonds fail to form in the 2A-like sequence, leaving the individual proteins separated.
In the field of genetic engineering, the virus is known for its 2A-like self-processing sequence of the capsid precursor protein. It allows for the generation of a multi-protein mRNA transcripts (polycistronic expression) by acting as a separator between proteins. Upon translation, peptide bonds fail to form in the 2A-like sequence, leaving the individual proteins separated.
- NCBI Taxonomy Browser - Thosea asigna virus [ English ]
- UniProtKB - Thosea asigna virus [ English ]
- [Journal of Insect Biotechnology and Sericology] Isolation of the Thosea asigna virus (TaV) from the epizootic Setothosea asigna larvae collected in South Sumatra and a study on its pathogenicity to Limacodidae larvae in Japan.pdf [ English ]
- [Journal of General Virology] A novel capsid expression strategy for Thosea asigna virus (Tetraviridae).pdf [ English ]
- [Plos ONE] Expression of Multiple Transgenes from a Single Construct Using Viral 2A Peptides in Drosophila [ English ]
- [Plos ONE] Self-cleaving peptides for expression of multiple genes in Dictyostelium discoideum [ English ]
| Record type | Field | Record(s) | |
|---|---|---|---|
| Genetic element | Donor organism (scientific name) | 1 | |