Risk assessment and risk management of LMOs with stacked genes or traits (part I)

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Introduction to the topic

Gene stacking (also known as gene pyramiding) is the process of combining two or more transgenes into an organism. Continue reading »

Suggested points for discussion

1. In addition to the steps taken when assessing the safety of single-transgene events, which elements should be considered when conducting risk assessments of LMOs with stacked genes?
2. How to assess potential interactions and synergism resulting from the presence of multiple transgenes? (e.g., altered toxicity to target or non-target organisms and any consequential impact on the development of resistance in target organisms, altered fitness of the genetically modified organisms acquiring the transgene combination through gene flow, etc.)
3. Further issues that are unique to this topic;
4. Recommendations for preparing risk assessment reports of LMOs with stacked genes or traits.

Selected readings

List of threads

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