Risk assessment and risk management of LMOs with stacked genes or traits (part I)

Dear Forum Participant,

Welcome to the Discussion Group on “Risk assessment and risk management of LMOs with stacked genes or traits”.

**The discussions within this group will take place from 1 to 14 December 2008.**

To assist in the discussions, the following is a non-exhaustive list of suggested points for discussion:

1. In addition to the steps taken when assessing the safety of single-transgene events, which elements should be considered when conducting risk assessments of LMOs with stacked genes?

2. How to assess potential interactions and synergism resulting from the presence of multiple transgenes? (e.g., altered toxicity to target or non-target organisms and any consequential impact on the development of resistance in target organisms, altered fitness of the genetically modified organisms acquiring the transgene combination through gene flow, etc.)

3. Further issues that are unique to this topic;

4. Recommendations for preparing risk assessment reports of LMOs with stacked genes or traits.

Also, an introduction to the topic, as well as a non-exhaustive list of suggested reading materials have been made available.

A short tutorial to assist the participants in posting messages and navigating through the Forum is available at http://bch.cbd.int/forum/tutorial_discgroup.pdf.

The CBD Secretariat thanks you for your active participation. Happy discussions!

The Biosafety Division

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