Rift Valley fever phlebovirus (RVFV) | BCH-ORGA-SCBD-115610 | Organism | Biosafety Clearing-House

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Organism (ORGA)
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published: 17 Jun 2020 last updated: 29 Jun 2020
Organism information
Rift Valley fever phlebovirus
Kingdom Orthornavirae
Phylum Negarnaviricota
Class Ellioviricetes
Order Bunyavirales
Family Phenuiviridae
Genus Phlebovirus
Species Rift Valley fever phlebovirus
  • Rift Valley fever virus
  • RVFV
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Additional classification
MP12
V (- ssRNA)
Viruses
Characteristics related to biosafety
First described in 1931 in the Rift Valley, Kenya.
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Most commonly seen in sub-Saharan Africa and Egypt. First observed on the Arabian Peninsula in 2000.
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Rift Valley fever is a viral zoonotic disease that mainly infects animals, but can also infect humans.  Transmission of the disease occurs via mosquito bites. The disease is most severe in animals, where it has  high mortality rates (~70 - 100%) in newborn ruminants, especially sheep and goats, and abortion in pregnant animals. Other pathologies in animals include fatal hemorrhagic fever, fetal malformation, encephalitis, ocular disease and hepatitis. In humans, the disease is normally mild. In rare cases, the disease is severe, causing neurological disorders, partial or complete blindness, hemorrhagic fever, or thrombosis. No human-to-human contact has been reported.
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  • Research
  • Vaccine
Additional Information
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Records referencing this document Show in search
Record type Field Record(s)
Genetic element Donor organism(s) 2