DD-Ø1951A-7 - Herbicide-tolerant cotton | BCH-LMO-SCBD-14783 | Living Modified Organism | Biosafety Clearing-House


Living Modified Organism (LMO)

Decisions on the LMO Risk Assessments  
published: 05 Jun 2006 last updated: 06 Feb 2013
Living Modified Organism identity
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
Herbicide-tolerant cotton
Line 19-51a was developed by recombinant DNA techniques to introduce a chimeric ALS gene, which encodes a sulfonylurea tolerant acetolactate synthase (ALS) enzyme.

The ALS enzyme produced in these transgenic cotton lines is a resistant form of the similar enzyme present in all plants, bacteria and fungi, and thereby confers resistance or tolerance to sulfonylurea herbicides.
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
Variety: Coker 312
Characteristics of the modification process
  • Agrobacterium-mediated DNA transfer
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
  • BCH-GENE-SCBD-15164-9 Acetohydroxy acid synthase gene (Chimeric) | Nicotiana tabacum (Tobacco, TOBAC )
    Protein coding sequence | Resistance to herbicides (Sulfonylurea)
  • BCH-GENE-SCBD-104672-4 Acetohydroxy acid synthase promoter | Nicotiana tabacum (Tobacco, TOBAC )
  • BCH-GENE-SCBD-100390-7 Acetohydroxy acid synthase gene terminator | Nicotiana tabacum (Tobacco, TOBAC )
  • BCH-GENE-SCBD-104673-2 Octopine Synthase Gene Leader Sequence | Agrobacterium tumefaciens (Agrobacterium)
    Leader Sequence
Southern blot analysis indicated that 2 copies of the construct were inserted in an inverted repeat orientation at one locus in the host genome. Additionally no components of the vector backbone were detected in the 19-51a line
LMO characteristics
  • Food
  • Feed
  • Fiber/textile
Detection method(s)
Additional Information
The chimeric S4-HrA gene present in 19-51a expresses a herbicide tolerant ALS, which allows the cotton plant to synthesize essential amino acids in the presence of sulfonylurea herbicides.