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Genetic element
(GENE)
published: 22 Jul 2008
last updated: 12 Feb 2021
5-enolpyruvylshikimate-3-phosphate synthase
EN
-
aroAEN
CS-aroa-ECOLX
EN
Protein coding sequence
No
-
BCH-ORGA-SCBD-14930-5 Organism Escherichia coli (ECOLX)Bacteria
EN
5-enolpyruvylshikimate-3-phosphate synthase
EN
Involved in EPSP biosynthesis. The aroA gene, which encodes 5-enolpyruvylshikimate-3-phosphate synthase , an enzyme of the common aromatic biosynthetic pathway, the enzyme participates in biosynthesis of the aromatic amino acids phenylalanine, tyrosine and tryptophan.
The enzyme is a target for herbicides as these amino acids are only synthesized in plants and microorganisms. Glyphosate acts as a competitive inhibitor for phosphoenolpyruvate, as substrate of EPSPS, and is used as a broad-spectrum systemic herbicide.
EN
The enzyme is a target for herbicides as these amino acids are only synthesized in plants and microorganisms. Glyphosate acts as a competitive inhibitor for phosphoenolpyruvate, as substrate of EPSPS, and is used as a broad-spectrum systemic herbicide.
EN
- Amplification of the aroA Gene from Escherichia coli Results in Tolerance to the Herbicide Glyphosate [ English ]
- GMC08001-002.pdf [ English ]
- UniProtKB - P0A6D3 (AROA_ECOLI) [ English ]
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