Glyphosate-N-Acteyltransferase gene | BCH-GENE-SCBD-48363 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)

published: 05 Mar 2009 last updated: 18 Feb 2021
General information
Glyphosate-N-Acteyltransferase gene
EN
CS-gat-BACLI
EN
Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
Glyphosate-N-Acteyltransferase
EN
Glyphosate-N-acetyltransferase expression in genetically modified plants may lead to detoxification of the glyphosate agent. This is brought about by the transfer of an acetyl group from acetyl CoA to the secondary amine group of glyphosate.

The resulting N-acetylglyphosate does not have the ability to inhibit the activity of the EPSPS enzyme, and the genetically modified plants are able to grow despite glyphosate treatment.
EN
Additional Information
Two modified versions of the GAT gene were developed using a DNA shuffling technique using the GAT coding sequences from 3 separate strains of B. licheniformis (Strains B6, 401 and DS3).
The two versions are known as GAT4621 and GAT4601.
EN
Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 9
Living Modified Organism Genetic elements construct 9