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Genetic element
(GENE)
last updated: 29 Dec 2025
Ferrochelatase
EN
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CS-hem15-KOMPAEN
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FECHEN
CS-hem15-PICPA
EN
Protein coding sequence
No
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BCH-ORGA-SCBD-106439-4 Organism Komagataella pastoris (Yeast)Fungi
EN
Ferrochelatase
EN
Ferrochelatase is the last enzyme of the heme biosynthetic pathway. It catalyzes the insertion of iron into protoporphyrin to form heme. It is synthesized in the cytoplasm as a 43-kDa protein that is proteolytically processed to 40 kDa as it is translocated into the mitochondrion.
EN
EN
- Optimizing cofactor availability for the production of recombinant heme peroxidase in Pichia pastoris [ English ]
- Heme and Hemoproteins [ English ]
- Heme Biosynthesis [ English ]
- Ferrochelatase: Mapping the Intersection of Iron and Porphyrin Metabolism in the Mitochondria ( ferrochelatase, heme, iron, porphyrin, metabolon, porphyria ) [ English ]
| Record type | Field | Record(s) | |
|---|---|---|---|
| Living Modified Organism | Introduced or modified genetic element(s) | 1 | |
| Living Modified Organism | Genetic elements construct | 1 | |
