Delta-6 elongase | Thalassiosira pseudonana - Centric diatom | BCH-GENE-SCBD-115633 | Genetic element | Biosafety Clearing-House

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Genetic element (GENE)

last updated: 08 Jul 2020
General information
Delta-6 elongase
EN
  • Δ6-elongase
    EN
  • Microsomal very long fatty acid elongase
    EN
  • ELO1
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D6E
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Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
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Delta-6 elongase is involved in the biosynthesis of polyunsaturated fatty acids and catalyzes the addition of two carbon-hydrogen groups to the carboxyl end of γ-linolenic acid, converting it to dihomo-γ-linolenic acid.

Reactions:
malonyl-CoA + γ-linolenoyl-CoA + H+ → 3-oxodihomo γ-linolenoyl-CoA + CO2 + coenzyme A

malonyl-CoA + stearidonoyl-CoA + H+ → (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + CO2 + coenzyme A
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Additional Information
Delta-6 elongase is a polypeptide of 272 amino acids approximately 32 kDa in size.
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