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Genetic element (GENE)
last updated: 16 Jul 2020
Protein coding sequence
Delta-4 desaturase catalyzes the creation of a double bond at the fourth position from the carboxyl end of docosapentaenoic acid (C22:5), converting it into docosahexaenoic acid (C22:6). It was also found that the another substrate for Δ4-desaturase, 22:4ω6, can be parallely desaturated to 22:5ω6.EN
Thraustochytrium sp. delta-4 desaturase encodes a polypeptide of 519 amino acids in length and approximately 59 kDa in size.EN
- Genome Sequencing and Analysis of Thraustochytriidae sp. SZU445 Provides Novel Insights into Polyunsaturated Fatty Acid biosynthesis pathway.pdf [ English ]
- GenBank - Sequence 19 from Patent WO2009016208 [ English ]
- Identification of a Delta 4 fatty acid desaturase from Thraustochytrium sp.pdf [ English ]
- The Δ4-desaturation pathway for DHA biosynthesis is operative in the human species - Differences between normal controls and children with the Zellweger syndrome.pdf [ English ]