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Genetic element
(GENE)
last updated: 29 Dec 2025
Protoporphyrinogen oxidase
EN
-
CS-hem14-KOMPAEN
-
PPG oxidaseEN
-
Protoporphyrinogen-IX oxidaseEN
-
PROTOXEN
CS-hem14-PICPA
EN
Protein coding sequence
No
-
BCH-ORGA-SCBD-106439-4 Organism Komagataella pastoris (Yeast)Fungi
EN
Protoporphyrinogen oxidase
EN
Protoporphyrinogen oxidase conducts the seventh step of the heme pathway. It oxidizes protoporphyrinogen IX to protoporphyrin IX by the removal of six hydrogen atoms. The resulting compound is an oxidized porphyrin, in contrast to the reduced porphyrinogen intermediates formed earlier.
EN
Protoporphyrinogen oxidase mutation in humans is associated with variegate porphyria, leading to increased photosensitivity and neurological symptoms.
- Optimizing cofactor availability for the production of recombinant heme peroxidase in Pichia pastoris [ English ]
- Heme and Hemoproteins [ English ]
- Heme Biosynthesis [ English ]
| Record type | Field | Record(s) | |
|---|---|---|---|
| Living Modified Organism | Introduced or modified genetic element(s) | 1 | |
| Living Modified Organism | Genetic elements construct | 1 | |
