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Genetic element
(GENE)
last updated: 01 Jun 2026
Downy Mildew Resistance 6
EN
-
Stdmr6-1EN
-
DMR6 susceptibility geneEN
CS-DMR6-SOLTU
EN
Protein coding sequence
Yes
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BCH-ORGA-SCBD-12106-6 Organism Solanum tuberosum (Potato, SOLTU)Crops
EN
Salicylic acid 5-hydroxylase
EN
Salicylic acid 5-hydroxylase (SA5H) involved in salicylic acid metabolism. Catalyzes the hydroxylation of salicylic acid to dihydroxybenzoic acid, contributing to salicylic acid homeostasis. Acts as a negative regulator of plant defense responses by reducing salicylic acid accumulation and suppressing the expression of defense-related genes.
EN
Gene knockout of Stdmr6-1 results in increased salicylic acid accumulation, activation of defense-related pathways, and enhanced resistance to the oomycete pathogen Phytophthora infestans. Field and controlled-environment studies have demonstrated reduced late blight severity in StDMR6-1 knockout potato lines.
- CRISPR/Cas9 genome editing of potato StDMR6-1 [ English ]
- создание векторных конструкций, несущих систему криспр-кася для направленного мутагенеза генов chl1 и dmrsh-1 Solanum tuberosum [ Russian ]
- Silencing susceptibility genes in potato hinders primary infection with Phytophthora infestans [ English ]
| Record type | Field | Record(s) | |
|---|---|---|---|
| Living Modified Organism | Introduced or modified genetic element(s) | 1 | |
