Domestic goat modified to produce human lactoferrin | BCH-LMO-SCBD-108045 | Living Modified Organism | Biosafety Clearing-House

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Living Modified Organism (LMO)
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Decisions on the LMO Risk Assessments  
last updated: 15 May 2015
Living Modified Organism identity
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Domestic goat modified to produce human lactoferrin
EN
rhLF Goat
No
A human lactoferrin coding sequence was incorporated into the goat genome resulting in the synthesis of the biologically active glycoprotein, rhLF, in the mammary gland of the transgenic goats.
EN
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
EN
Characteristics of the modification process
hLf3, hLf5
EN
  • Microinjection
Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
  • BCH-GENE-SCBD-108043-1 Recombinant human lactoferrin coding sequence | Homo sapiens (HUMAN)
    Protein coding sequence | Production of medical or pharmaceutical compounds (human or animal)
  • BCH-GENE-SCBD-108044-1 Beta-casein gene promoter | Capra aegagrus hircus (Domestic goat, Goat, CAPHI)
    Promoter
EN
LMO characteristics
EN
  • Research
Detection method(s)
EN
Additional Information
EN
Records referencing this document Show in search
Record type Field Record(s)
Risk Assessment generated by a regulatory process Living modified organism(s) 2
Country's Decision or any other Communication Living modified organism(s) 2